A recent analysis of 24 different studies showed there was a significant association between mothers who smoke in early pregnancy and the development of a cleft lip in the baby (a gap in the upper lip) and/or cleft palate (a hole in the roof of the mouth). A woman has approximately a 30 percent increased risk of having a baby with a cleft lip and/or cleft palate and a 20 percent increased risk of having a baby with a cleft palate if she smokes. This is another reason why women planning to be come pregnant or who are newly pregnant should try to cease or reduce smoking.
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